Patient Proning Resources
Proning patients with Acute Respiratory Distress Syndrome may increase oxygenation and reduce mortality, but the practice is difficult to perform manually.
Large prospective, randomized trial shows prone therapy improved survival in patients with ARDS or hypoxemia
DATA FROM CLINICAL STUDY: “Prone Positioning in Severe Acute Respiratory Distress Syndrome”. C Guerin et al. N Engl J Med 2013; 368: 2159-2169
- 466 patient multicenter, prospective, randomized control trial over a 28 day horizon – and extrapolated to 90 days
- Recruited patients all presented with severe ARDS: PaO2:FiO2 ratio <150mm Hg, with FiO2 >= 0.6, PEEP of >= 5cm water and tidal volume of 6 mL/kg of predicted body weight
- Prone therapy summary: Avg. 4+/-4 sessions per patient; Avg. 17+/-3 hours per prone session
Prone vs. supine patient mortality
Mortality of prone patients @ day 28 was significantly lower (16%) than supine group (P<0.001)
Prone vs supine PaO2/FiO2
PaO2/FiO2 ratio improved during prone therapy sessions.